Case Report: Recurrent Miller Fisher Syndrome

We report the case of a 47-year-old male who presented with numbness and difficulty speaking and was diagnosed with Miller Fisher Syndrome, a variant Guillain-Barré Syndrome. The differential diagnosis for numbness and speech difficulty is broad and includes brain stem stroke, Wernicke encephalopathy, botulism, myasthenia gravis, among others. Although Miller Fisher Syndrome is rare, certain factors such as the of tumor necrosis factor-alpha antagonists may predispose a patient to the disease and its recurrence. As discovery of new tumor necrosis factor-alpha antagonists continues it will likely result in more presentations of Guillain-Barré Syndrome and its variants to the emergency department.

Publication Details

Journal
Rowan Digitals Works (Rowan University)
Published
2025-05-01
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
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article

Case Report: Recurrent Miller Fisher Syndrome

Rowan Digitals Works (Rowan University)
Peripheral Neuropathies and Disorders
article

Case Report: Recurrent Miller Fisher Syndrome

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Abstract

We report the case of a 47-year-old male who presented with numbness and difficulty speaking and was diagnosed with Miller Fisher Syndrome, a variant Guillain-Barré Syndrome. The differential diagnosis for numbness and speech difficulty is broad and includes brain stem stroke, Wernicke encephalopathy, botulism, myasthenia gravis, among others. Although Miller Fisher Syndrome is rare, certain factors such as the of tumor necrosis factor-alpha antagonists may predispose a patient to the disease and its recurrence. As discovery of new tumor necrosis factor-alpha antagonists continues it will likely result in more presentations of Guillain-Barré Syndrome and its variants to the emergency department.

Rowan Digitals Works (Rowan University)
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Peripheral Neuropathies and Disorders
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