Якість життя та психоемоційний стан вагітних із гіперпроліферативними захворюваннями матки в динаміці обстеження за період 2018–2024 рр.

Quality of life (QL) is an indicator widely used worldwide to assess the physical, mental and social state of a person’s health, which is especially important for the expectant mother. During pregnancy, the most widely discussed area of QL is physical health. However, this does not diminish the important role of the psychological state and social relationships in pregnant womenThe objective: to study the QL and psycho-emotional state in pregnant women with urerine hyperproliferative diseases (HPD).Materials and methods. By means of a questionnaire during 2018–2024, 680 pregnant women with uterine HPD were examined. They were observed and delivered in the Department of purulent-inflammatory diseases in obstetrics and were undergoing treatment and examination in the Department of rehabilitation of women’s reproductive function or in the women’s consultation of the SI “Ukrainian Center of Maternity and Childhood of the National Academy of Medical Sciences of Ukraine”. The main group (MG) included 517 pregnant women with a combinated forms of HPD, which included: uterine endometriosis (adenomyosis), uterine leiomyoma (UL), endometrial polyps and/or glandular endometrial hyperplasia which were diagnosed before pregnancy. 82 pregnant women without uterine HPD (absent of adenomyosis, UL, endometrial polyps and/or glandular endometrial hyperplasia before pregnancy) included into the comparison group (CpmG). 81 pregnant women without uterine HPD (absent of adenomyosis, UL, endometrial polyps and/or glandular endometrial hyperplasia before pregnancy) and without pregnancy complications were included into the control group (CtrlG). The study is prospective, cohort randomized. Psychometric research methods were used, in particular, assessment of health-related QL by MOS SF-36 (Medical Outcomes Study Short Form) and the QL assessment scale (O. S. Chaban) and psychosomatic disorders using the Hospital Anxiety and Depression Scale (HADS).Results. QL indicators in pregnant women with uterine HPD significantly differed from those in healthy women and pregnant women without uterine HPD, which indicates negative changes in both physical health and mental health, especially due to such QL parameters as role-emotional functioning and vital activity. After 2022, 82% of pregnant women in the MG answered the question “Were you very nervous?” – “Most of the time” (until 2022 – 39%), and 76% of patients answered the question “Did you feel down or depressed?” – “All the time” (until 2022 – 27%). A low level of QL was found in 14% of pregnant women with uterine HPD, which indicates dissatisfaction with their lives, the presence of significant problems and those that are difficult to solve, and the lack of joy from life, which is perceived as a difficult struggle with an uncertain and mostly negative future. This indicator is 2.3 times higher than the similar one in the CtrlG (p < 0.05) and by 3% in the CpmG.Conclusions. In pregnant women with uterine HPD (UL, adenomyosis, endometrial polyps and/or endometrial hyperplasia), such indicators of QL as psychological health (according to the SF-36 scale), role-emotional functioning and vital activity are especially reduced.