Thermal clines and disease blights: Exploring multi-stressor impacts on evolutionary potential

Predicting how organisms adapt to rapidly changing environments is a central challenge in global-change biology. Climate-driven stressors, such as rising temperatures, interact with emerging and re-emerging diseases that impose strong selective pressures, and sometimes severe population bottlenecks, that may erode genetic diversity and constrain future adaptation. However, it remains unclear to what extent adaptation to one stressor (disease) compromises the capacity to respond to another (temperature). To quantify how adaptation to multiple interacting stressors impacts future adaptive potential, we developed evolutionary to track adaptation in a population experiencing novel thermal and disease pressures. Here we quantify evolutionary trade-offs of adapting to disease in a warming climate.