Evaluation of Biological Activity of Curcumin Extracted From Curcuma Longa L

Curcuma Longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Curcumin, a yellow pigment present in the Indian spice turmeric (associated with curry powder), has been linked with suppression of inflammation; angiogenesis; tumorigenesis; diabetes; diseases of the cardiovascular, pulmonary, and neurological systems, of skin, and of liver; loss of bone and muscle; depression; chronic fatigue; and neuropathic pain. . Because of the multiple therapeutic activities attributed to curcumin, the present study aimed to evaluate the anti-bacterial activity of aquatic and ethanolic extracts of Curcuma Longa against different bacterial isolates. In the present study in vitro, test confirmed the antibacterial activity of turmeric extract against five different bacterial species isolated from patients with chronic urinary tract infections, including (Escherichia coli, Staphylococcus aureus, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumonia ). The antibacterial activity was measured by agar well diffusion method. The extract of Curcuma Longa L . showed antibacterial activity against all the test bacterial isolates. The results of the antibacterial activity of the ethanolic extract of Curcuma Longa rhizomes showed that the highest inhibition zone was observed in P. aeruginosa ( 16 mm), K. pneumonia (15 mm) S. aureus and E.coli (10 mm ) , A. baumannii (8 mm), While The results of the aquatic extract showed that the highest inhibition zone was observed in P. aeruginosa ( 14 mm), K. pneumonia (13 mm) S. aureus and E.coli ( 8 mm ) , A. baumannii ( no result).