Fibromiyalji Hastalarında Merkezi Duyarlılık ve Vücut Farkındalığının Belirleyicisi Olarak Hastalık Aktivitesinin Rolü: Kesitsel Bir Çalışma

Purpose: The present study aimed to identify the influence of disease activity on central sensitization (CS) and body awareness in fibromyalgia syndrome (FMS) patients.Materials and Methods: Forty-five patients with FMS (mean age: 45.9 (6.9) years, median disease duration: 3 (2-6) years) were participated this cross-sectional study. Disease activity was assessed using the Fibromyalgia Impact Questionnaire (FIQ) and higher score was considered high disease activity. The Central Sensitization Inventory (CSI) was performed for central sensitivity. Body awareness levels were evaluated with the Body Awareness Questionnaire (BAQ). Visual Analogue Scale (VAS) was used to identify pain severity. Simple linear regression analyses were used to determine which independent variables could explain disease activity.Results: The mean FIQ and BAQ were 53.4 and 90 points, respectively. The median VAS and CSI were 8 cm and 52 point, respectively. The CS is positive in 82.2% of all patients. FIQ was moderately correlated with the VAS score (r=0.445, R2=0.198, p=0.002) and is highly correlated with CSI (r=0.539, R2=0.291, p<0.001). There was no significant correlation between FIQ and BAQ (p=0.791). The results of the simple linear regression analysis presented that VAS explained 19.8% of the the disease activity. FIQ (r=0.445, p=0.002) significantly predicted pain severity. Additionally, The CSI explained 29.1% of the disease activity and FIQ (r=0.539, p<0.001) significantly predicted CS.Conclusion: High disease activity negatively impacts CS and body awareness in FMS patients. Clinicians should consider a multimodal biopsychosocial perspective in addition to routine treatments in the management of patients with high disease activity.