Development of a stress response framework for understanding SOGIE refugee health

As an increasing number of individuals flee persecution on the basis of sexual orientation and gender identity expression (SOGIE), Canada has become a prominent destination for SOGIE refugees. The chronic stressors encountered by this marginalized population remain insufficiently studied, particularly in relation to physical health outcomes. This qualitative study investigates the cumulative health impacts of chronic stress among SOGIE refugees through the application of a cell-to-society framework, underpinned by Minority Stress Theory (MST). The study seeks to develop a SOGIE-specific stress response framework that theorizes the processes by which social and environmental stressors become biologically embedded, thereby contributing to elevated allostatic load. In doing so, it extends the existing literature on the intersections of stress with both physical and mental health outcomes. The findings aim to inform evidence-based policy interventions that more effectively address the unique health challenges confronting SOGIE refugees in Canada.