Childhood Traumas and Depressive Symptoms: The Moderating Role of Anxiety Sensitivity

Kumru Şenyaşar Meterelliyoz,1 Özlem Baş Uluyol2 1Department of Psychiatry, Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey; 2Department of Psychiatry, Sancaktepe Şehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, TurkeyCorrespondence: Kumru Şenyaşar Meterelliyoz, Department of Psychiatry, Bakirkoy Prof. Dr. Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Zuhuratbaba Mah. Akıl Hastanesi Cd. 25/2, Bakırköy, Istanbul, 34147, Turkey, Tel +902124091515, Email [email protected]: Depression is one of the most common public health problems. Considering the frequency of childhood trauma in people with depressive symptoms, determining mediating factors is important in understanding the relationship between them. Our study aimed to evaluate the mediating effect of anxiety sensitivity, one of the cognitive structures that plays a role in the etiology and maintenance of psychopathologies, on depression symptoms of childhood traumas.Patients and Methods: The study included 110 participants aged between 18 and 65, diagnosed with depression, and applied to the psychiatry outpatient clinic. Of the participants, 35 were male and 75 were female. The majority of participants were in the 18– 25 age group (39.1%), followed by a smaller percentage in the 25– 35 age group (32.7%). The Beck Depression Inventory (BDI-I), Childhood Trauma Questionnaire (CTQ), and Anxiety Sensitivity Index (ASI-3) were administered to participants between 15 February and 15 April 2024.Results: When the sample was examined according to the history of depressive symptoms, it was found that the score of the cognitive subscale of ASI-3 and the scores of the physical neglect, emotional neglect, and emotional abuse subscales of the CTQ were significantly higher in the group with depressive symptoms. When the mediating effect of the scores of “Emotional neglect”, “Physical neglect”, and “Emotional abuse” subscales of CTQ, and the score of “Cognitive” subscale of ASI-3 score was examined with regression models, it was found that the history of emotional neglect and abuse in childhood predicted depressive symptoms through the cognitive sub-group of AS.Conclusion: In our study, it was shown that childhood trauma, which could cause a person to evaluate stressful life events as more depressogenic and the formation of negative cognitions about themselves and the world, predicted the severity and occurrence of depressive symptoms through fear of cognitive dysfunction.Keywords: childhood trauma, depression, anxiety sensitivity