A Comparison of Acute Blood Glucose Response to 2% Lactaid Milk vs. 2% Regular Milk in a Non-Diabetic Population

Rising rates of diabetes and prediabetes have increased interest in how common foods affect blood glucose. This randomized, triple-blinded controlled trial compared the acute glycemic response to 2% regular milk versus 2% Lactaid milk in non-diabetic adults. Fifty participants consumed 500 mL of either milk type after fasting, and blood glucose was measured at baseline, then at 15, 30, 45, and 60 minutes post-consumption. Linear mixed model analysis showed no significant interaction by age or gender. However, borderline significant differences were observed at 15 minutes (p = 0.0524) and 30 minutes (p = 0.0740), with slightly faster and higher glucose rises in the Lactaid group. These findings suggest that hydrolyzed lactose (glucose and galactose) in Lactaid milk may accelerate glucose absorption. Although not statistically significant, the results may have implications for those managing blood glucose levels. Further studies using continuous glucose monitoring and varied populations could help refine dietary recommendations regarding milk consumption and glycemic control.