Peri-İmplantitis de İnterlökin 6 (rs1800795) ve Diğer Proinflamatuar Sitokin olan İnterlökinlerin Gen Polimorfizmlerinin Etkileri: Kısa bir İnceleme

A disease evaluated in medicine can be a predictor for a disease in dentistry, and a disease in dentistry can be a precursor to a disease in medicine. An example is the relationship between cellular immune factors, which are a field of the immune system, and “peri-implant diseases” evaluated in the dentistry literature. The increase in the quality of life and life span in people necessitates the research of new treatment methodologies for oral and dental health in the oral rehabilitation process. Peri-implant diseases are one of the important issues to investigate. There are many factors such as the genetic structure of the individual, and microbiological and environmental factors that determine the success and effectiveness of implant treatment. Knowing the infrastructure of immune-related proinflammatory cytokines in the peri-implantitis disease that we have examined can contribute to the effectiveness of treatment approaches related to this disease. In this context, we aimed to present a brief review of studies evaluating the effectiveness of the IL-6 rs1800795 gene polymorphism, an important proinflammatory cytokine, and the IL-1, IL-8 and IL-17 gene polymorphisms, which are other proinflammatory cytokines evaluated in the interleukin class, on peri-implantitis and therefore periodontal diseases.