Synthetic Data Generation with Large Language Models for Improved Depression Prediction

Automatic depression detection is gaining traction at the intersection of psychology and machine learning, but concerns over data privacy and scarcity persist. We propose a pipeline using Large Language Models (LLMs) to generate synthetic data that enhances depression prediction while addressing ethical concerns. Starting from recorded clinical transcripts, our chain-of-thought prompting involves two steps: the generation of a synopsis and sentiment analysis from the original transcript, and the generation of synthetic data based on these summaries and a new depression score. The resulting synthetic data not only performs well in terms of utility and fidelity, but also balances the severity distribution in training datasets, improving prediction of depression intensity. Our method offers a practical solution to augmenting limited, sensitive data while preserving statistical integrity. This framework provides a robust framework for advancing mental health research and applications without compromising patient privacy.

Publication Details

Journal
eScholarship (California Digital Library)
Published
2025-01-01
Primary Topic
Mental Health via Writing
Type
article
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article

Synthetic Data Generation with Large Language Models for Improved Depression Prediction

eScholarship (California Digital Library)
Mental Health via Writing
article

Synthetic Data Generation with Large Language Models for Improved Depression Prediction

article en

Abstract

Automatic depression detection is gaining traction at the intersection of psychology and machine learning, but concerns over data privacy and scarcity persist. We propose a pipeline using Large Language Models (LLMs) to generate synthetic data that enhances depression prediction while addressing ethical concerns. Starting from recorded clinical transcripts, our chain-of-thought prompting involves two steps: the generation of a synopsis and sentiment analysis from the original transcript, and the generation of synthetic data based on these summaries and a new depression score. The resulting synthetic data not only performs well in terms of utility and fidelity, but also balances the severity distribution in training datasets, improving prediction of depression intensity. Our method offers a practical solution to augmenting limited, sensitive data while preserving statistical integrity. This framework provides a robust framework for advancing mental health research and applications without compromising patient privacy.

eScholarship (California Digital Library)
Openalex Percentile: Top 43%
Mental Health via Writing
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Synthetic Data Generation with Large Language Models for Improved Depression Prediction · eScholarship (California Digital Library) (2025) | TGRS Research Map | TGRS