Synthesis of Dipeptides with Evaluation for Antimicrobial Activity

For this poster presentation, the antimicrobial properties of a dipeptide will be tested, along efficient routes of synthesis of said dipeptide. The antimicrobial properties of some peptides and their synthesis are fields of research of great interest to pharmaceutical scientists. A dipeptide is formed by linking one amino acid to another. To ensure a uniform product, the C-terminus of one amino acid will be protected using a fairly novel esterification method described in by Turhanen et al in "Green and Efficient Esterification Method Using Dried Dowex H +/NaI Approach," while the N-terminus of the other will be protected using a Boc- group. Then, the peptide will be synthesized and evaluated for effectiveness, being compared to other synthesized dipeptides.