Nanofibrous Coatings of Poly(Lactic Acid) and NanoHydroxyapatite for Enhanced Biocompatibility of Titanium Implants

Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano-hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite-coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.

Publication Details

Journal
IRIS Research product catalog (Sapienza University of Rome)
Published
2025-01-01
Primary Topic
Pharmaceutical studies and practices
Type
article
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article

Nanofibrous Coatings of Poly(Lactic Acid) and NanoHydroxyapatite for Enhanced Biocompatibility of Titanium Implants

IRIS Research product catalog (Sapienza University of Rome)
Pharmaceutical studies and practices
article

Nanofibrous Coatings of Poly(Lactic Acid) and NanoHydroxyapatite for Enhanced Biocompatibility of Titanium Implants

article en

Abstract

Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano-hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite-coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.

IRIS Research product catalog (Sapienza University of Rome)
Openalex Percentile: Top 38%
Pharmaceutical studies and practices
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