Infección grave de piel y tejidos blandos en paciente con linfoma de Hodgkin metastásico en manejo paliativo

Severe skin and soft tissue infections are common complications in patients with Hodgkin lymphoma (HL), especially those in the advanced stages of the disease who are receiving palliative treatment. HL is a type of lymphoma characterized by the proliferation of abnormal lymphocytes, and its treatment, which includes chemotherapy and immunotherapy, involves significant immunosuppression, which increases the risk of infections. Infections can evolve rapidly in these patients and present atypical features, complicating diagnosis and management. The objective of this report is to describe the case of a 73-year-old patient with metastatic HL on palliative treatment who developed a severe skin and soft tissue infection, which evidenced the challenge in the management of infections in immunocompromised patients. Despite receiving targeted antimicrobial therapy and surgical drainage, the patient presented a progressive clinical deterioration due to persistent infection and refractory sepsis, culminating in multiorgan failure. This case highlights the importance of a multidisciplinary approach that considers both antimicrobial management and comprehensive patient care, prioritizing symptomatic management and commu-nication with family members in poor prognostic scenarios