Ventricular Interdependent Phenotype of Mixed Cpc-Pulmonary Hypertension and HFpEF with Normal Left Atrium: Impact on CPET Metrics and Clinical Outcome

Among 45 CpcPH/heart failure with preserved ejection fraction participants, 11 with normal left atrium (compared to 34 with abnormal left atrium, p < 0.05 for all) had low left ventricle (LV) transmural pressure (2.9 ± 2.4 vs. 6.2 ± 2.9 mmHg), and increased right ventricle (RV):LV ratio (2.41 ± 1.09 vs. 1.46 ± 0.66) and interventricular septal angle (149 ± 8 vs. 136 ± 10), indicating exaggerated ventricular interdependence from a dilated RV

Publication Details

Journal
The Medicine Forum
Published
2024-10-11
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Ventricular Interdependent Phenotype of Mixed Cpc-Pulmonary Hypertension and HFpEF with Normal Left Atrium: Impact on CPET Metrics and Clinical Outcome

The Medicine Forum
Pulmonary Hypertension Research and Treatments
article

Ventricular Interdependent Phenotype of Mixed Cpc-Pulmonary Hypertension and HFpEF with Normal Left Atrium: Impact on CPET Metrics and Clinical Outcome

article en

Abstract

Among 45 CpcPH/heart failure with preserved ejection fraction participants, 11 with normal left atrium (compared to 34 with abnormal left atrium, p < 0.05 for all) had low left ventricle (LV) transmural pressure (2.9 ± 2.4 vs. 6.2 ± 2.9 mmHg), and increased right ventricle (RV):LV ratio (2.41 ± 1.09 vs. 1.46 ± 0.66) and interventricular septal angle (149 ± 8 vs. 136 ± 10), indicating exaggerated ventricular interdependence from a dilated RV

The Medicine Forum
Good health and well-being
Openalex Percentile: Top 43%
Pulmonary Hypertension Research and Treatments
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Ventricular Interdependent Phenotype of Mixed Cpc-Pulmonary Hypertension and HFpEF with Normal Left Atrium: Impact on CPET Metrics and Clinical Outcome · The Medicine Forum (2024) | TGRS Research Map | TGRS