Revealing Telomerase Expression in Sea Star Embryos: Implications for Regeneration and Anti-Aging Mechanisms

Telomerase, an enzyme crucial for the maintenance of telomere length and cellular longevity, plays an important role in cellular aging, cancer, and regenerative processes. Cellular aging is a complex biological process that involves the progressive decline in cellular functions and regenerative capacity. This research focuses on in-situ bio staining techniques to investigate telomerase expression in aging tissue. Using targeted colorimetric probes, we were able to detect telomerase mRNA expression in various tissue samples in sea stars. Our findings are consistent with the hypothesis that sea stars age in a healthy manner and this may be due to widespread telomerase expression. Continued study of telomere biology in sea stars may offer potential therapeutic strategies for age-related disease in humans.

Publication Details

Journal
Scholarly Commons (University of the Pacific)
Published
2025-04-07
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
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article

Revealing Telomerase Expression in Sea Star Embryos: Implications for Regeneration and Anti-Aging Mechanisms

Scholarly Commons (University of the Pacific)
Telomeres, Telomerase, and Senescence
article

Revealing Telomerase Expression in Sea Star Embryos: Implications for Regeneration and Anti-Aging Mechanisms

article en

Abstract

Telomerase, an enzyme crucial for the maintenance of telomere length and cellular longevity, plays an important role in cellular aging, cancer, and regenerative processes. Cellular aging is a complex biological process that involves the progressive decline in cellular functions and regenerative capacity. This research focuses on in-situ bio staining techniques to investigate telomerase expression in aging tissue. Using targeted colorimetric probes, we were able to detect telomerase mRNA expression in various tissue samples in sea stars. Our findings are consistent with the hypothesis that sea stars age in a healthy manner and this may be due to widespread telomerase expression. Continued study of telomere biology in sea stars may offer potential therapeutic strategies for age-related disease in humans.

Scholarly Commons (University of the Pacific)
Life below water
Openalex Percentile: Top 43%
Telomeres, Telomerase, and Senescence
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Revealing Telomerase Expression in Sea Star Embryos: Implications for Regeneration and Anti-Aging Mechanisms · Scholarly Commons (University of the Pacific) (2025) | TGRS Research Map | TGRS