Case 339

A 66-year-old male patient with a background history of hypertension and no history of liver disease was found to have mildly deranged liver function test results as part of his annual hypertension review. Clinical examination findings were unremarkable, the patient was afebrile (36.8 °C), and other vital observations were within normal limits. Full blood count and urea and creatinine levels were within normal limits; however, liver function tests revealed a mildly elevated alanine aminotransferase level of 61 IU/L (1.02 µkat/L) (reference range, 0–40 IU/L [0–0.67 µkat/L]), and a mildly elevated γ-glutamyltransferase level of 52 IU/L (0.88 µkat/L) (reference range, 0–50 IU/L [0–0.83 µkat/L]). The patient subsequently underwent US examination of the abdomen, which revealed a large liver lesion in an otherwise normal liver with no imaging features of cirrhosis. MRI of the liver was performed for further characterization (Fig 1). The patient subsequently underwent resection of the large mass and surgical pathology. Surveillance MRI was performed 4 months after surgery (Fig 2).

Publication Details

Journal
White Rose Research Online (University of Leeds, The University of Sheffield, University of York)
Published
2025-03-01
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Case 339

White Rose Research Online (University of Leeds, The University of Sheffield, University of York)
Liver Disease Diagnosis and Treatment
article

Case 339

article en

Abstract

A 66-year-old male patient with a background history of hypertension and no history of liver disease was found to have mildly deranged liver function test results as part of his annual hypertension review. Clinical examination findings were unremarkable, the patient was afebrile (36.8 °C), and other vital observations were within normal limits. Full blood count and urea and creatinine levels were within normal limits; however, liver function tests revealed a mildly elevated alanine aminotransferase level of 61 IU/L (1.02 µkat/L) (reference range, 0–40 IU/L [0–0.67 µkat/L]), and a mildly elevated γ-glutamyltransferase level of 52 IU/L (0.88 µkat/L) (reference range, 0–50 IU/L [0–0.83 µkat/L]). The patient subsequently underwent US examination of the abdomen, which revealed a large liver lesion in an otherwise normal liver with no imaging features of cirrhosis. MRI of the liver was performed for further characterization (Fig 1). The patient subsequently underwent resection of the large mass and surgical pathology. Surveillance MRI was performed 4 months after surgery (Fig 2).

White Rose Research Online (University of Leeds, The University of Sheffield, University of York)
Good health and well-being
Openalex Percentile: Top 40%
Liver Disease Diagnosis and Treatment
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Case 339 · White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (2025) | TGRS Research Map | TGRS