Evaluation of cell plating efficiency on polymer surfaces for organ-on-a-chip applications

Due to their many benefits, polymers have gained popularity recently, particularly in the biomedical industry. SU-8 and polydimethylsiloxane (PDMS) in particular have drawn notice for their advanta-geous qualities, such as chemical stability and biocompatibility. Proper cellular function in biological environments depends on effective cell-surface interactions. A new method of surface modification that involves coating Poly-L-lysine (PLL) and applying oxygen plasma treatment appears to be promis-ing in improving the adhesion of HEK 293 cells to PDMS and SU-8 surfaces.