Alkolik olmayan yağlı karaciğer hastalığında brakiyal arterin akım aracılı dilatasyon yetersizliği ve artmış karotid intima kalınlığı

Aims: This study aimed to evaluate endothelial dysfunction and vascular changes in non-alcoholic fatty liver disease (NAFLD) patients by measuring carotid intima-media thickness (C-IMT) and flow-mediated dilation (FMD).Methods: This prospective observational cohort study included 51 biopsy-proven NAFLD patients and 21 healthy controls. Endothelial function was assessed using high-resolution ultrasonography to measure brachial artery FMD and C-IMT. Patients with hepatotoxic drug use, significant alcohol consumption, or other liver diseases were excluded. Demographic data, body-mass index (BMI), and waist circumference were recorded. Statistical analyses were conducted using SPSS, with significance set at p