АНАЛІЗ СУЧАСНИХ ПІДХОДІВ ДО СТВОРЕННЯ СТИМУЛ-ЧУТЛИВИХ ПОЛІМЕРНИХ МАТРИЦЬ ДЛЯ БІОМЕДИЧНИХ ЗАСТОСУВАНЬ

This paper presents an analytical review of current approaches to the development of polymer matrices responsive to physicochemical stimuli, with a focus on their biomedical applications. Various synthesis methods are considered, including radical, photo-initiated, combinatorial, and microfluidic polymerization, as well as the use of biopolymers and hybrid systems. Strategies for reducing production costs, scaling up synthesis, and improving functional properties are discussed. Examples of stimuli-responsive polymer matrices applied in drug delivery systems, regenerative medicine, tissue engineering, and biosensors are analyzed. The most promising directions for further development are outlined, based on efficiency, biocompatibility, and economic feasibility.