Pain Relief and Protection of Corns, Calluses and Bunions Using COMPEED® Foot Care Hydrocolloid Plasters: A Prospective Non-Interventional Study in Primary Care/Community Pharmacies

Jérôme Zakka Bajjani,1 Pascale Auzou,1 Hubert Paniez,1 Maria Katsogiannou,2 Véronique Chapalain,2 Carole Pierre,2 Sandra Wiederkehr,2 Rémi Gauchoux,2 Matthieu Gauthier,3 Cécile Artus-Arduise1 1Laboratoire HRA Pharma, A Perrigo company, Chatillon, France; 2ICTA PM, Fontaine les Dijon, France; 3Totum Pharmaciens, Paris, FranceCorrespondence: Jérôme Zakka Bajjani, Laboratoire HRA Pharma, A Perrigo company, Chatillon, France, Email [email protected]: Pathologic hyperkeratosis due to skin thickness increase includes corn, callous, and bunion. These conditions can cause important pain and discomfort. Treatment relies on eliminating the cause of friction and/or rubbing. Moreover, hydrocolloid occlusive dressings rehydrate hard skin, leading to maceration, facilitating removal of dead skin. Our goal was to further confirm real-life clinical performance and benefits of COMPEED® Foot Care plasters in providing pain/discomfort relief, protection and cushioning of corns, calluses and bunions.Patients and Methods: This was a non-interventional, longitudinal, multi-center investigation, conducted from July 2021 until February 2022, during which participants were enrolled in 36 community pharmacies in France. Eligible participants were ≥ 18 years old at enrolment, presented painful corn, callous and/or bunion on at least one foot, accepted to buy from the participating pharmacist at least one box of targeted COMPEED® Foot Care plasters, to be used according to their instructions for use.Results: Overall, 417 participants gave their consent to participate in the study, and analysis was performed on 391 participants: 199 with corn, 106 with callous, 87 with bunion, whose median age was, respectively, 55.0, 59.0 and 55.0 years old (overall ranging 20.0 to 94.0 years old). Among participants with either of the 3 conditions, 21.7– 37.9% reported instant pain/discomfort relief upon plaster application and an increasing number of participants with corns, calluses or bunions reported pain/discomfort elimination over the 21-days follow-up period. Significant increases in pressure relief and cushioning were also observed during follow-up in all 3 conditions. Median duration of plasters was 3 days. At study end, 66.0% of participants with calluses and up to 73.0% with corns reported their condition was removed.Conclusion: This investigation demonstrated and confirmed COMPEED® Foot Care plasters clinical benefits in pain/discomfort and pressure relief, cushioning against rubbing/friction of corns, calluses and bunions, and adhesion to skin, in the general population.Keywords: hydrocolloid plasters, foot corn, foot callus, bunion, cushioning, pain/discomfort relief