Research Papar on Formulation and Evalition of Herbal Tablet for Hypertension

The present study focuses on the formulation and evaluation of a herbal tablet intended for the management of hypertension, utilizing the medicinal properties of Ocimum sanctum (Tulsi), Coleus forskolin(Coleus), and Allium sativum (Garlic). These herbs are well-documented for their antihypertensive, cardioprotective, and antioxidant activities. The herbal extracts were standardized and incorporated into tablet formulations using direct compression methods with suitable excipients. Pre-compression parameters like bulk density, tapped density, Carr’s index and Hausner’s ratio were evaluated to ensure good flow properties. The compressed tablets were assessed for weight variation, hardness, friability, disintegration time, and in vitro drug release. Stability studies were also conducted under accelerated conditions. The formulated tablets demonstrated acceptable physical characteristics and a sustained release of active constituents, indicating their potential efficacy in the management of hypertension. Thus, the study successfully developed a herbal tablet combining traditional knowledge with modern pharmaceutical techniques to offer a natural alternative for blood pressure regulation.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-06
DOI
https://doi.org/10.5281/zenodo.15609740
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
Field-Weighted Citation Impact
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article

Research Papar on Formulation and Evalition of Herbal Tablet for Hypertension

Zenodo (CERN European Organization for Nuclear Research)
Phytochemicals and Medicinal Plants
article

Research Papar on Formulation and Evalition of Herbal Tablet for Hypertension

article en

Abstract

The present study focuses on the formulation and evaluation of a herbal tablet intended for the management of hypertension, utilizing the medicinal properties of Ocimum sanctum (Tulsi), Coleus forskolin(Coleus), and Allium sativum (Garlic). These herbs are well-documented for their antihypertensive, cardioprotective, and antioxidant activities. The herbal extracts were standardized and incorporated into tablet formulations using direct compression methods with suitable excipients. Pre-compression parameters like bulk density, tapped density, Carr’s index and Hausner’s ratio were evaluated to ensure good flow properties. The compressed tablets were assessed for weight variation, hardness, friability, disintegration time, and in vitro drug release. Stability studies were also conducted under accelerated conditions. The formulated tablets demonstrated acceptable physical characteristics and a sustained release of active constituents, indicating their potential efficacy in the management of hypertension. Thus, the study successfully developed a herbal tablet combining traditional knowledge with modern pharmaceutical techniques to offer a natural alternative for blood pressure regulation.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 36%
Phytochemicals and Medicinal Plants
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Research Papar on Formulation and Evalition of Herbal Tablet for Hypertension · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS