Herbal Approach to Chronic Kidney Disease: A Study on Multi-Herb Powder Formulation

The present study focuses on the formulation and evaluation of a polyherbal powder composed of Punarnava, Ashwagandha, Gokshura, Tulsi, and Amla, traditionally known for their beneficial effects on kidney health. The objective was to develop a natural formulation aimed at supporting the management of chronic kidney disease (CKD) through a safe and effective herbal approach. Each plant ingredient was selected based on its pharmacological properties such as anti-inflammatory, diuretic, antioxidant, and nephroprotective effects. Preliminary phytochemical analysis of the prepared polyherbal powder formulation revealed the presence of alkaloids, glycosides, tannins, amino acids, and saponins in all the herbal components. All herbal samples were confirmed to contain alkaloids, glycosides, tannins, amino acids, and saponins. components. Physicochemical parameters including bulk density, tapped density, angle of repose, Carr’s index, Hausner’s ratio, and loss on drying were evaluated to assess the flowability and quality of the powder. The results indicated acceptable ranges for all tested parameters, ensuring the formulation’s suitability for further development.[1] This study demonstrates the potential of combining multiple herbs in a powdered form to support kidney function and provides a foundation for further pharmacological evaluation and clinical research.[1].