IMMUNOLOGICAL PARAMETERS IN TOXIC ALCOHOLIC LIVER LESIONS

Alcohol is one of the most common toxins that have a negative effect on liver tissue, and young age is no exception to the risk group, given the popularization of alcohol abuse in this age group. Alcohol metabolism in the liver is accompanied by the formation of acetaldehyde, an active metabolite contributing to cellular damage, inflammation, and the development of fibrosis [1; 3]. Early diagnosis is carried out using laboratory tests, ultrasound and, in some cases, magnetic resonance imaging, which allows you to determine the degree of tissue damage. Treatment is based on the complete exclusion of alcohol, the appointment of antioxidants such as vitamin E and methylsulfonylmethane, and the use of drugs that stabilize the membrane function of hepatocytes.