Triune Energy Compartment Hypothesis and the Chimeric Evolution of Vertebrates
This paper proposes the Triune Genome Hypothesis, which frames the vertebrate genome as a composite of three functional modules corresponding to the ectodermal (neural), mesodermal (musculoskeletal), and endodermal (visceral) systems.The theory is supported by evidence of endogenous retroviral insertions, whole-genome duplications, and viral gene integration in marine environments, contributing to the rapid and chimeric emergence of the vertebrate lineage.The work also introduces the Triune Energy Compartment Hypothesis, linking the anatomical and developmental modularity with metabolic independence — as reflected in glycogen storage specialization in the liver, muscles, and astrocytes.This framework offers a new synthesis for understanding vertebrate origins as a system-level genomic and physiological integration event.
Institutions
- Kappa Omicron Nu Honor Society (US)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2025-08-04
- DOI
- https://doi.org/10.5281/zenodo.16738148
- Primary Topic
- Developmental Biology and Gene Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00