Heart failure in middle biological age: diagnostic methods and therapeutic approaches

Heart failure (HF) is a complex and progressive disease in which the heart is unable to supply the body with sufficient blood and oxygen. Recently, there has been increasing attention to the study of HF in people of middle biological age, when the disease may be latent or manifest itself in a form other than the classic symptoms. The diagnosis of heart failure in this age group represents a significant challenge, as the manifestations of the disease may be subtle and overlap with other age-related diseases. The main methods of diagnosing HF include clinical observations, analyses, instrumental investigations (ECG, echocardiography, chest radiography) and laboratory tests such as determination of natriuretic peptide levels. Effective diagnosis requires a comprehensive approach that includes evaluation of the patient's complaints, historical data, and the use of modern technologies such as magnetic resonance imaging. Therapeutic approaches to the treatment of middle-aged HFare varied and include drug treatment (ACE inhibitors, beta-blockers, mineralocorticoid receptor antagonists) as well as non-drug methods such as lifestyle changes, weight control and diet. In some cases, surgical intervention such as pacemakers or heart transplantation is indicated. It is also important to consider co-morbid conditions such as hypertension, diabetes mellitus and coronary heart disease, which require an individualized approach to treatment. The article discusses methods of diagnosis and treatment of heart failure in middle-aged patients, as well as the role of prevention and early diagnosis in improving the quality of life and increasing the life expectancy of this category of patients.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-22
DOI
https://doi.org/10.5281/zenodo.14911431
Primary Topic
Heart Failure Treatment and Management
Type
article
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article

Heart failure in middle biological age: diagnostic methods and therapeutic approaches

Zenodo (CERN European Organization for Nuclear Research)
Heart Failure Treatment and Management
article

Heart failure in middle biological age: diagnostic methods and therapeutic approaches

article en

Abstract

Heart failure (HF) is a complex and progressive disease in which the heart is unable to supply the body with sufficient blood and oxygen. Recently, there has been increasing attention to the study of HF in people of middle biological age, when the disease may be latent or manifest itself in a form other than the classic symptoms. The diagnosis of heart failure in this age group represents a significant challenge, as the manifestations of the disease may be subtle and overlap with other age-related diseases. The main methods of diagnosing HF include clinical observations, analyses, instrumental investigations (ECG, echocardiography, chest radiography) and laboratory tests such as determination of natriuretic peptide levels. Effective diagnosis requires a comprehensive approach that includes evaluation of the patient's complaints, historical data, and the use of modern technologies such as magnetic resonance imaging. Therapeutic approaches to the treatment of middle-aged HFare varied and include drug treatment (ACE inhibitors, beta-blockers, mineralocorticoid receptor antagonists) as well as non-drug methods such as lifestyle changes, weight control and diet. In some cases, surgical intervention such as pacemakers or heart transplantation is indicated. It is also important to consider co-morbid conditions such as hypertension, diabetes mellitus and coronary heart disease, which require an individualized approach to treatment. The article discusses methods of diagnosis and treatment of heart failure in middle-aged patients, as well as the role of prevention and early diagnosis in improving the quality of life and increasing the life expectancy of this category of patients.

Zenodo (CERN European Organization for Nuclear Research)
First Pavlov State Medical University of St. Petersburg (RU), Pirogov Russian National Research Medical University (RU), Dagestan State Medical University (RU), Astrakhan State Medical University (RU), Dagestan State University (RU), Saratov State Medical University (RU)
Openalex Percentile: Top 38%
Heart Failure Treatment and Management
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Heart failure in middle biological age: diagnostic methods and therapeutic approaches · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS