Anti-Helminthic Syrup by Herbal Extract

Helminthiasis is a most common parasitic infection in the world. It may produce a serious risk to public health. Anthelmintic activity in paediatrics refers to use of drugs to treat parasitic worm infections in children. The various types of marketing preparations are available in the market. Finding innovative anthelmintics with a unique mode of action is imperative as a side effect and developing resistance to already prescribed anthelmintic medication pose a serious threat. Hence, the current study was carried out with aim to prepare and evaluate the anthelmintic activity with pineapple extract. The bromelain enzyme present in pineapple which is show anti-parasitic activity on nematodes. It has been used for centuries in medicines. It is also used as dietary supplement. Bromelain shows antihelmintic activity. The activity is done on earthworms which are comes under the class of nematodes. Here we done the test to determine the stability of the syrup. We performed PH test, turbidity, visual, physical stability, crystal growth and viscosity test. The evaluation study helps to know the safety and efficacy of syrup. Here we learn the formulation and evaluation of pineapple syrup on earthworms. We observe the antihelmintic activity as well as paralysis and death of the earthworms.