Neurobrucellosis: A Case Series

Introduction Brucellosis has been an important zoonotic disease globally. Since Brucella can infect and survive without inducing a massive inflammatory response, this Bacteria was labelled as “stealth pathogen.” Its protean and diverse clinical presentation can mimic other infectious and Non infectious diseases, posing challenges to physicians in reaching a diagnosis, and merited the label “disease of mistakes”. The complications of brucellosis are common and can involve a wide range of body organs and localization, neuro brucellosis being among the most serious ones. Awareness about the disease and the use of appropriate Brucella -specific tests can expedite the accurate diagnosis. Medical literature is flooded with numerous studies from different parts of the world, especially Those Endemic with brucellosis, addressing the clinical and complication aspects of this most widespread zoonotic disease. Among a considerable number of papers published on this topic there is a shortlist that we can consider as landmark in this field [ 1 , 2-7 , 8-11 , 12 , 13 , 14 ]. On a more specific aspect dealing with neuro brucellosis, a couple of studies on this critical complication have been well noted in the literature [ 15 , 16 ]. Though the clinical and complication aspects have not changed, brucellosis remains a significant zoonotic disease that is emerging or re-emerging in many parts of the world. In addition, the inclusion of Brucella spp. in the potential biological weapon lists of most authorities has renewed interest in this these pathogens [ 17 ]. However, the improved knowledge and awareness, as well as the introduction of newer technology and tests, have helped detect and reveal more of such episodes in a short time [ 18 , 19 ].

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-08-30
DOI
https://doi.org/10.5281/zenodo.15429556
Primary Topic
Brucella: diagnosis, epidemiology, treatment
Type
article
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article

Neurobrucellosis: A Case Series

Zenodo (CERN European Organization for Nuclear Research)
Brucella: diagnosis, epidemiology, treatment
article

Neurobrucellosis: A Case Series

article en

Abstract

Introduction Brucellosis has been an important zoonotic disease globally. Since Brucella can infect and survive without inducing a massive inflammatory response, this Bacteria was labelled as “stealth pathogen.” Its protean and diverse clinical presentation can mimic other infectious and Non infectious diseases, posing challenges to physicians in reaching a diagnosis, and merited the label “disease of mistakes”. The complications of brucellosis are common and can involve a wide range of body organs and localization, neuro brucellosis being among the most serious ones. Awareness about the disease and the use of appropriate Brucella -specific tests can expedite the accurate diagnosis. Medical literature is flooded with numerous studies from different parts of the world, especially Those Endemic with brucellosis, addressing the clinical and complication aspects of this most widespread zoonotic disease. Among a considerable number of papers published on this topic there is a shortlist that we can consider as landmark in this field [ 1 , 2-7 , 8-11 , 12 , 13 , 14 ]. On a more specific aspect dealing with neuro brucellosis, a couple of studies on this critical complication have been well noted in the literature [ 15 , 16 ]. Though the clinical and complication aspects have not changed, brucellosis remains a significant zoonotic disease that is emerging or re-emerging in many parts of the world. In addition, the inclusion of Brucella spp. in the potential biological weapon lists of most authorities has renewed interest in this these pathogens [ 17 ]. However, the improved knowledge and awareness, as well as the introduction of newer technology and tests, have helped detect and reveal more of such episodes in a short time [ 18 , 19 ].

Zenodo (CERN European Organization for Nuclear Research)
Innovative Research (United States) (US)
Openalex Percentile: Top 44%
Brucella: diagnosis, epidemiology, treatment
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