Pulmonary metastases revealing a mixed germ cell tumor with a predominant yolk sac tumor component: A case report

Yolk sac tumor of the testis is rare in adults. Its diagnosis is histological, reproducing an extra-embryonic structure (endodermal sinus tissue). It can be present alone or associated with another component, thus forming a mixed germ cell tumor. Treatment involves orchiectomy and chemotherapy in extratesticular stages. Lymph node dissection is indicated if residual masses persist. These tumors are characterized by a poor prognosis at an advanced metastatic stage. However, we report the clinical case of a 69-year-old man who presented with pulmonary metastases from a mixed germ cell tumor of the testis with a predominant Yolk Sac Tumor component, treated by orchiectomy, chemotherapy, and lymph node dissection.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-10-30
DOI
https://doi.org/10.5281/zenodo.15019920
Primary Topic
Testicular diseases and treatments
Type
article
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article

Pulmonary metastases revealing a mixed germ cell tumor with a predominant yolk sac tumor component: A case report

Zenodo (CERN European Organization for Nuclear Research)
Testicular diseases and treatments
article

Pulmonary metastases revealing a mixed germ cell tumor with a predominant yolk sac tumor component: A case report

article en

Abstract

Yolk sac tumor of the testis is rare in adults. Its diagnosis is histological, reproducing an extra-embryonic structure (endodermal sinus tissue). It can be present alone or associated with another component, thus forming a mixed germ cell tumor. Treatment involves orchiectomy and chemotherapy in extratesticular stages. Lymph node dissection is indicated if residual masses persist. These tumors are characterized by a poor prognosis at an advanced metastatic stage. However, we report the clinical case of a 69-year-old man who presented with pulmonary metastases from a mixed germ cell tumor of the testis with a predominant Yolk Sac Tumor component, treated by orchiectomy, chemotherapy, and lymph node dissection.

Zenodo (CERN European Organization for Nuclear Research)
Cadi Ayyad University (MA)
No poverty
Openalex Percentile: Top 42%
Testicular diseases and treatments
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Pulmonary metastases revealing a mixed germ cell tumor with a predominant yolk sac tumor component: A case report · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS