PATHOPHYSIOLOGICALLY AND CLINICALLY SUBSTANTIATE CHANGES IN INTERLEUKIN DYNAMICS IN DIABETIC MACRO - AND MICROANGIOPATHIC WITH PATIENTS

Determination of the effectiveness of ozone therapy and its pathomorphological properties with new pharmacological drugs for the treatment of purulent necrotic process of the foot. By studying the dynamics of anti-inflammatory cytokine levels: analysis of the need and possibility of immunoprotection by studying cytokine status in IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, TNF-α, INF-γ patients on the development and recurrence of purulent-necrotic processes of DFS.