Anti -Asthmatic Activity of An Ethanolic Extract of Entire Plant of Euphorbia Hirta from the Pharmacognostical, Pharmacological and Phytochemical Screening - An Research

To evaluate the anti-asthmatic activity of Euphorbia hirta through pharmacological assessment and phytochemical screening. The research focuses on identifying bioactive compounds responsible for its medicinal properties and scientifically validating its efficacy. The study involves the collection and authentication of Euphorbia hirta, followed by extraction using the Soxhlet apparatus with ethanol. Pharmacognostical analysis, including macroscopic and microscopic studies, was conducted to identify the plant’s physical and anatomical characteristics. Phytochemical screening was performed to detect the presence of alkaloids, flavonoids, saponins, terpenoids, tannins, steroids, amino acids, and volatile oils. The chemical composition was further analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). In vitro anti-asthmatic activity was assessed through cell viability assays using THP-1 cell lines. The pharmacognostical analysis confirmed the morphological and anatomical features of Euphorbia hirta. Phytochemical screening indicated the presence of several bioactive compounds with potential therapeutic benefits. GC-MS analysis identified key chemical constituents. In vitro studies demonstrated the plant extract's anti-inflammatory and anti-asthmatic effects, supporting its traditional use in respiratory ailments. The findings validate the anti-asthmatic potential of Euphorbia hirta, highlighting its efficacy in treating respiratory disorders. The presence of bioactive compounds suggests its potential as a natural alternative for asthma management. Further in vivo studies and clinical trials are recommended to establish its therapeutic applications.