A Review on Analytical Methods for Vildagliptin and Metformin in Combination

It is an antidiabetic medication belongs to dipeptidyl peptidase-4(DPP-4) enzyme inhibitor classof drug. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.Vildagliptin works by increasing the release of insulin from the pancreas and decreasing the hormones that raise bloodsugar levels.METFORMIN : It is the first line drug of choice for the treatment of type 2 diabetes particularly in overweight andobese people with normal Kidney function. The review highlights the variety of analytical methods such as UVspectroscopy, high performance liquid chromatography (HPLC), GC (Gas chromatography), LCMS and Highperformance thin layer chromatography (HPTLC) for the estimation of Vildagliptin and Metformin in combination inpharmaceuticals.