Development of UV Spectroscopic Method of Dapagliflozin with Some Validation Parameter

This research compiles information on the development of analytical methods for estimating Dapagliflozin, which will be valuable for future research on this drug and its impurities. The literature survey covers various analytical methods such as UV, RP-HPLC, HPTLC, and other techniques reported for Dapagliflozin, both alone and in combination with other drugs. The analysis of published data indicates that only a UV spectroscopic method (calibration curve method) has been reported for estimating Dapagliflozin in fixed-dose combination. Each technique is evaluated for its sensitivity, specificity, and applicability in different matrices, including pharmaceutical formulations and biological fluids. The research also discusses the advantages, challenges, and recent advancements in these methods, providing a detailed comparison to guide researchers and practitioners in selecting the most appropriate technique for their specific needs.