Analytical Method Development & Estimation of Salbutamol Sulphate in Inhaler Dosage from by Using UV, FTIR And HPLC

Salbutamol is almost exclusively metabolised by conjugation to a 4’-o-sulphate ester in the intestinal wall and liver. A second minor metabolite has been reported3-5. Side effects of salbutamol were reported to be minimal and well tolerated. One of the earliest instrumental techniques for analysis is UV-VIS spectroscopy. Many different types of materials can be characterized using UV-V is spectroscopy. FTIR is used to analyse the small molecules or complex molecules. Wide range of sample types such as solid, liquid and gas can be checked from about 4000-400 cm-1. Fourier transform infrared (FTIR) spectroscopy represents a modern and popular technique that addressed IR spectroscopy as a powerful and reliable analytical technique. The using the method of UV, FTIR and HPLC to find out the absorbance wavelength and percentage purity of salbutamol sulphate.