Formulation Science of Effervescent Tablets: From Manufacturing to Release Kinetics

Oral dosage forms are the most often used method of administering medication, they have certain drawbacks, such as a slower rate of absorption. By consuming liquid dose forms, this can be avoided. The majority of APIs, however, have been discovered to be unstable in liquid formulation. An alternate approach to creating a dosage form that can accelerate the dispersion and degradation of medications is the effervescent technique. Because of their quick onset of action and ease of administration, effervescent tablets are growing in popularity. Usually, they comprise acidic substances and carbonates or bicarbonates that react rapidly with water to release carbon dioxide, enhance API solubility, and hide flavor. The benefits and drawbacks of effervescent tablets, effervescent reactions, active ingredients that can be formulated, Effervescent Dosage Form Manufacturing, Effervescent system for Geriatric and Paediatric Population, Process, Formulation methods, Raw material, tablet evaluation and Release kinetic modeling of effervescent tablets are all covered in this article.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-06
DOI
https://doi.org/10.5281/zenodo.15350690
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Formulation Science of Effervescent Tablets: From Manufacturing to Release Kinetics

Zenodo (CERN European Organization for Nuclear Research)
Drug Solubulity and Delivery Systems
article

Formulation Science of Effervescent Tablets: From Manufacturing to Release Kinetics

article en

Abstract

Oral dosage forms are the most often used method of administering medication, they have certain drawbacks, such as a slower rate of absorption. By consuming liquid dose forms, this can be avoided. The majority of APIs, however, have been discovered to be unstable in liquid formulation. An alternate approach to creating a dosage form that can accelerate the dispersion and degradation of medications is the effervescent technique. Because of their quick onset of action and ease of administration, effervescent tablets are growing in popularity. Usually, they comprise acidic substances and carbonates or bicarbonates that react rapidly with water to release carbon dioxide, enhance API solubility, and hide flavor. The benefits and drawbacks of effervescent tablets, effervescent reactions, active ingredients that can be formulated, Effervescent Dosage Form Manufacturing, Effervescent system for Geriatric and Paediatric Population, Process, Formulation methods, Raw material, tablet evaluation and Release kinetic modeling of effervescent tablets are all covered in this article.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 55%
Drug Solubulity and Delivery Systems
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.