Formulation Science of Effervescent Tablets: From Manufacturing to Release Kinetics
Oral dosage forms are the most often used method of administering medication, they have certain drawbacks, such as a slower rate of absorption. By consuming liquid dose forms, this can be avoided. The majority of APIs, however, have been discovered to be unstable in liquid formulation. An alternate approach to creating a dosage form that can accelerate the dispersion and degradation of medications is the effervescent technique. Because of their quick onset of action and ease of administration, effervescent tablets are growing in popularity. Usually, they comprise acidic substances and carbonates or bicarbonates that react rapidly with water to release carbon dioxide, enhance API solubility, and hide flavor. The benefits and drawbacks of effervescent tablets, effervescent reactions, active ingredients that can be formulated, Effervescent Dosage Form Manufacturing, Effervescent system for Geriatric and Paediatric Population, Process, Formulation methods, Raw material, tablet evaluation and Release kinetic modeling of effervescent tablets are all covered in this article.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2025-05-06
- DOI
- https://doi.org/10.5281/zenodo.15350690
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00