INVESTIGATING THE EFFECTS OF AQUEOUS EXTRACT OF DOSE DEPENDENT JATROPHA TANJORENSIS (CHAYA) LEAF ON HEAMATOLOGICAL PARAMETERS OF MALE WISTER RATS: A DOSE-DEPENDENT ANALYSIS

Abstract: Medicinal plants are the sources of many scientific drugs of the modern world and thus the leaves of Jatropha tanjorensis have been found to have important application both in traditional medicine and as edible vegetable in Nigeria soups. This study aimed to evaluate the effect of aqueous extract of dose- dependent Jatropha tanjorensis (chaya) leaf on heamatological parameters of male wistar rats. Total of forty (40) male wister rats weighing 130-150g (about 12 weeks old) were grouped into five groups of 8 rats each, (group A to E), Group A served as negative control (just water and feed only), while Group B (Low dose of Jatropha tanjorensis, 200mg/kg), Group C (Medium dose of Jatropha tanjorensis , 400mg/kg), Group D, (High dose of Jatropha tanjorensis, 600mg/kg), Group E (Positive control, just folic acid drugs and feed only). Haematological indices were accessed using automated system (Sysmax Xt-2000i). The results revealed that all the haematological indices, red blood cells, haemoglobin, packed cell volume, white blood cell count MCV, MCH, and MCHC all had increase in values compared with group A and were stastically significantly (P<0.05). Keywords: Heamatological, haemoglobin, Jatropha tanjorensis, Medicinal, Parameters, Sysmax Xt-2000i, Wistar rats. Title: INVESTIGATING THE EFFECTS OF AQUEOUS EXTRACT OF DOSE DEPENDENT JATROPHA TANJORENSIS (CHAYA) LEAF ON HEAMATOLOGICAL PARAMETERS OF MALE WISTER RATS: A DOSE-DEPENDENT ANALYSIS Author: Dim Catherine Nicholate, Ezeokafor Emmanuel Nonso, Ajaegbu Obinna Chinedu, Enendu Angela Chika, Nsofor Cordelia Uche, Afuberoh Francis Chukwudi, Anyiam Kennedy Ekenedirichukwu, Amasi Mitchell Onyinyechukwu International Journal of Recent Research in Life Sciences (IJRRLS) ISSN 2349-7823 Vol. 12, Issue 2, April 2025 - June 2025 Page No: 12-15 Paper Publications Website: www.paperpublications.org Published Date: 02-June-2025 DOI: https://doi.org/10.5281/zenodo.15575785 Paper Download Link (Source) https://www.paperpublications.org/upload/book/INVESTIGATING%20THE%20EFFECTS%20OF%20AQUEOUS%20EXTRACT%20OF%20DOSE-02062025-3.pdf