Open Source Spatial Reactomics (OSSpRe) Workflow for Trapped Ion Mobility Spectrometry (TIMS) Coupled with High Resolution Mass Spectrometry Imaging

High resolution mass spectrometry imaging lipidomics RAW data of mouse pancreas were collected using the Bruker timsTOF fleX with MALDI and TIMS at a 10 μm spatial resolution. Data was collected in positive mode utilizing a 300 to 1300 m/z window and a 1/K0 from 0.5 to 1.6 V-s/cm2. Additional instrument parameters included a ramp time of 100 ms, an accumulation time of 100 ms, a 100% duty cycle, and a ramp rate of 9.08 Hz.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-07-11
DOI
https://doi.org/10.5281/zenodo.15863066
Primary Topic
Mass Spectrometry Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Open Source Spatial Reactomics (OSSpRe) Workflow for Trapped Ion Mobility Spectrometry (TIMS) Coupled with High Resolution Mass Spectrometry Imaging

Zenodo (CERN European Organization for Nuclear Research)
Mass Spectrometry Techniques and Applications
article

Open Source Spatial Reactomics (OSSpRe) Workflow for Trapped Ion Mobility Spectrometry (TIMS) Coupled with High Resolution Mass Spectrometry Imaging

article en

Abstract

High resolution mass spectrometry imaging lipidomics RAW data of mouse pancreas were collected using the Bruker timsTOF fleX with MALDI and TIMS at a 10 μm spatial resolution. Data was collected in positive mode utilizing a 300 to 1300 m/z window and a 1/K0 from 0.5 to 1.6 V-s/cm2. Additional instrument parameters included a ramp time of 100 ms, an accumulation time of 100 ms, a 100% duty cycle, and a ramp rate of 9.08 Hz.

Zenodo (CERN European Organization for Nuclear Research)
Jackson Laboratory (US)
Openalex Percentile: Top 55%
Mass Spectrometry Techniques and Applications
DOIOpen Access PDFOpenAlex
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