A State-Of-The-Art Overview of Quinoxaline, Its Derivatives, and Applications

A significant type of heterocycle molecules are quinoxaline derivatives, in which N substitutes for some of the carbon atoms in the naphthalene ring. It is made up of the fusion of two aromatic rings, pyrazine and benzene, and has the chemical formula C8H6N2. Although it is uncommon in nature, it is simple to synthesize them. The State of the Art will be discussed in this review, along with an overview of the advancements in understanding the structure and mechanism of quinoxaline and its derivatives, as well as their related industrial, medicinal, and biological importance. Numerous biomedical uses, including the treatment of chronic and metabolic illnesses and antibacterial properties, can be obtained by altering the structure of quinoxaline.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-11
DOI
https://doi.org/10.5281/zenodo.15193133
Primary Topic
Synthesis and Biological Evaluation
Type
article
Field-Weighted Citation Impact
0.00
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article

A State-Of-The-Art Overview of Quinoxaline, Its Derivatives, and Applications

Zenodo (CERN European Organization for Nuclear Research)
Synthesis and Biological Evaluation
article

A State-Of-The-Art Overview of Quinoxaline, Its Derivatives, and Applications

article en

Abstract

A significant type of heterocycle molecules are quinoxaline derivatives, in which N substitutes for some of the carbon atoms in the naphthalene ring. It is made up of the fusion of two aromatic rings, pyrazine and benzene, and has the chemical formula C8H6N2. Although it is uncommon in nature, it is simple to synthesize them. The State of the Art will be discussed in this review, along with an overview of the advancements in understanding the structure and mechanism of quinoxaline and its derivatives, as well as their related industrial, medicinal, and biological importance. Numerous biomedical uses, including the treatment of chronic and metabolic illnesses and antibacterial properties, can be obtained by altering the structure of quinoxaline.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 51%
Synthesis and Biological Evaluation
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A State-Of-The-Art Overview of Quinoxaline, Its Derivatives, and Applications · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS