THE EFFECTS OF PIPER NIGRUM (BLACK PEPPER) EXTRACT ON THYMOCYTE CELLS

Black pepper (Piper nigrum) has been extensively used in the food industry as a spice and in traditional medicine to improve digestion and appetite. It is rich in flavonoids, polyphenols, alkaloids, and tannins. Recent studies have demonstrated its antioxidant properties, anti-aging effects, and natural antibiotic characteristics. However, the mechanisms by which black pepper extract affects cellular structures, specifically membranes, remain inadequately studied. This study investigates the effects of black pepper extract on the membrane regulatory processes of rat thymocyte cells under hypoosmotic stress conditions.