A Review of Adverse Effects of Banned Drugs in India

A Number of drugs that are banned in the Indian market. The most potable feature is that use of these drugs is regularly using lung term implication for our Physical health. Some of the common ones that we easily available and people Ne frequently without doctor’s prescription are D- cold, Nimesulide and Analgin The decision to ban drugs based on the risk versus benefit ratio evaluated through post-marketing surveillance and the Adverse Drug Reaction Reporting System. Pharmaceutical negligence among doctors can lead to hazardous effects on the general health of a patient. Some drugs may cause adverse effects only within comb nod with particular drugs in such cases, only the fixed dose combination is banned and not the individual drugs. The drugs which am found unsafe in post marketing surveillance are banned by regulatory authorities. Banned drugs still available in developing countries like India due to lack of Law enforcement physician awareness and drug control authorizes fails to inform all hospital of the status of medicine India is a major hub of banned drug. Many of the banned drugs are available as over the counter drugs and people consume them unaware and cause damage to one self. Government should be ordered to damage theme cheap drugs in proper manner. And are, India’s pharmacovigilance, effort has to be scaled up rapidly. People should say top selling banned drugs. Mefenamic acid is a fenamate nonsteroidal anti-inflammatory (NSAID) drug that belongs to the anthranilic acid derivative family, which is used for several years for pain management. Mefenamic acid is a cyclooxygenase (cox-1 and cox-2) inhibitor and blocks the production of intracellular prostaglandins that are important in pain and inflammatory pathways. Like most NSAID, Mefenamic acid is generally well tolerated but side effects an include headache, dizziness, nausea, diarrhea, abdominal discomfort, heartburn, peripheral edema and hypersensitivity reactions. Other analgesics and NSAID’s avoid concomitant use of two or more NSAID as this may increase the risk of adverse effects. Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life- threatening adverse drug-induced reaction with an estimated mortality of 10%.