A Comparative Evaluation of Annona Muricata L. (Graviola/Soursop) Extract With 0.2% Chlorhexidine Gluconate in Prevention of Plaque and Gingivitis

Abstract Natural products have drawn in significant interest for their pharmacological properties as well as in dental practises. Annona muricata L., or soursop, is a tropical tree whose foliage includes bioactive substances like flavonoids and polyphenols, perceived for their antibacterial and anticancerous properties. The qualities demonstrate that soursop leaf extract may act as a powerful substitute for commercially available mouthwashes. This examination tried to evaluate the viability of Annona muricata leaf extract in tending to plaque development and gingivitis, comparing benefits with that of an economically available 0.2% chlorhexidine gluconate mouthwash, A randomized clinical trial including 40 participants were included, divided into 2 groups . Test group utilized a mouthwash containing Annona muricata leaf extract, while control group utilized a 0.2% chlorhexidine gluconate mouthwash for 15 days. The discoveries showed that the two treatments actually diminished plaque and gingival aggravation, exhibiting comparative adequacy across the two groups. Members utilizing the Annona muricata mouthwash showed less incidental effects, including oral distress and taste adjustments, frequently connected to chlorhexidine. This shows that Annona muricata leaf extract might act as a more secure and more satisfactory choice for oral hygiene maintainence. Notwithstanding these reassuring discoveries, the review's restricted example size and brief term need more examination. Broad examinations with delayed follow-up lengths are expected to extensively assess the drawn out adequacy and efficacy of Annona muricata extract. All in all, Annona muricata leaf extract has huge commitment as a characteristic option in contrast to chlorhexidine gluconate for the management of plaque and gingivitis, showing less unfriendly impacts.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-30
DOI
https://doi.org/10.5281/zenodo.15210195
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
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article

A Comparative Evaluation of Annona Muricata L. (Graviola/Soursop) Extract With 0.2% Chlorhexidine Gluconate in Prevention of Plaque and Gingivitis

Zenodo (CERN European Organization for Nuclear Research)
Oral microbiology and periodontitis research
article

A Comparative Evaluation of Annona Muricata L. (Graviola/Soursop) Extract With 0.2% Chlorhexidine Gluconate in Prevention of Plaque and Gingivitis

article en

Abstract

Abstract Natural products have drawn in significant interest for their pharmacological properties as well as in dental practises. Annona muricata L., or soursop, is a tropical tree whose foliage includes bioactive substances like flavonoids and polyphenols, perceived for their antibacterial and anticancerous properties. The qualities demonstrate that soursop leaf extract may act as a powerful substitute for commercially available mouthwashes. This examination tried to evaluate the viability of Annona muricata leaf extract in tending to plaque development and gingivitis, comparing benefits with that of an economically available 0.2% chlorhexidine gluconate mouthwash, A randomized clinical trial including 40 participants were included, divided into 2 groups . Test group utilized a mouthwash containing Annona muricata leaf extract, while control group utilized a 0.2% chlorhexidine gluconate mouthwash for 15 days. The discoveries showed that the two treatments actually diminished plaque and gingival aggravation, exhibiting comparative adequacy across the two groups. Members utilizing the Annona muricata mouthwash showed less incidental effects, including oral distress and taste adjustments, frequently connected to chlorhexidine. This shows that Annona muricata leaf extract might act as a more secure and more satisfactory choice for oral hygiene maintainence. Notwithstanding these reassuring discoveries, the review's restricted example size and brief term need more examination. Broad examinations with delayed follow-up lengths are expected to extensively assess the drawn out adequacy and efficacy of Annona muricata extract. All in all, Annona muricata leaf extract has huge commitment as a characteristic option in contrast to chlorhexidine gluconate for the management of plaque and gingivitis, showing less unfriendly impacts.

Zenodo (CERN European Organization for Nuclear Research)
International Association for Dental Research (US)
Openalex Percentile: Top 44%
Oral microbiology and periodontitis research
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