CLINICAL AND ENDOCRINE EVALUATION OF HORMONAL THERAPY IN THE MANAGEMENT OF POLYCYSTIC OVARY SYNDROME (PCOS): A LONGITUDINAL OBSERVATIONAL STUDY

Polycystic Ovary Syndrome (PCOS) represents one of the most common endocrine disorders affecting women of reproductive age. With a global prevalence estimated at around 10–15%, PCOS manifests in a spectrum of clinical features including hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology. Additionally, it is associated with significant metabolic complications, including insulin resistance, type 2 diabetes mellitus, dyslipidemia, and obesity. The heterogeneity of PCOS presentation and progression necessitates individualized treatment plans.