Critical Analysis of Lipid Profile in Chronic Obstructive Pulmonary Disease and Its Correlation with Disease Severity

This paper aims to assess the lipid composition of people with COPD (chronic obstructive pulmonary disease) by comparing it with the severity of the illness. A study group of 50 patients suffering from COPD and another group with 50 normal adults who were not having any chronic medical condition and were not receiving any treatment that affects lipids formation in their bodies were chosen. The majority of cases were males (88%) and over 60 years, with a mean age of 60.09 ± 8.06 years for males and female ages averaging 56 ± 2.56 years. The aim of the study is to analysis outcomes which describe the differences in serum lipid levels between COPD patients and controls; these included low-density lipoprotein (S.LDL), triglycerides (S.TG), and cholesterol. In patients with COPD, it was observed that the levels of S.LDL, S.TG, and cholesterol were considerably higher, while serum high-density lipoprotein (S.HDL) levels were lower (P-value < 0.05). However, any relationship between the lipid profile and severity of COPD was not statistically significant (P-Value > 0.05). According to the results obtained, S.LDL was higher among people with COPD compared to the control group, while S.HDL was lower. In contrast, S.LDL, Cholesterol, and S.TG demonstrated a marked increase in severe and very severe stages of COPD as compared to moderate stages but, differently from those of moderate stages did not show any statistically significant differences