Implementation of adapted volume distribution in the basic dynamic Hickling Model

Abstract: Accurate modeling of lung dynamics is crucial for understanding respiratory physiology and developing effective treatments. This study extends the basic dynamic Hickling model by introducing an adapted volume distribution, resulting in a more accurate simulation of lung mechanics. The incorporation of adapted volume distribution improves the model’s ability to simulate dynamic pressure changes during mechanical ventilation and addresses the overestimation of end-inspiratory pressure. Compared to the basic model, the enhanced version demonstrates significant improvements in representing physiological behavior.

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Publication Details

Journal
Repository of Futwangen University of Applied Sciences (Furtwangen University)
Published
2024-12-01
DOI
https://doi.org/10.5281/zenodo.14278666
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00

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article

Implementation of adapted volume distribution in the basic dynamic Hickling Model

Repository of Futwangen University of Applied Sciences (Furtwangen University)
Inhalation and Respiratory Drug Delivery
article

Implementation of adapted volume distribution in the basic dynamic Hickling Model

article en

Abstract

Abstract: Accurate modeling of lung dynamics is crucial for understanding respiratory physiology and developing effective treatments. This study extends the basic dynamic Hickling model by introducing an adapted volume distribution, resulting in a more accurate simulation of lung mechanics. The incorporation of adapted volume distribution improves the model’s ability to simulate dynamic pressure changes during mechanical ventilation and addresses the overestimation of end-inspiratory pressure. Compared to the basic model, the enhanced version demonstrates significant improvements in representing physiological behavior.

Repository of Futwangen University of Applied Sciences (Furtwangen University)
Furtwangen University (DE)
Horizon 2020 Framework Programme
Openalex Percentile: Top 44%
Inhalation and Respiratory Drug Delivery
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