Reproductive Outcomes in Patients with Infertility and Insulin Resistance

Infertility defined as the inability of a couple to achieve conception after one year of sexual intercourse without contraceptive protection, or after 6 months in patients older than 35 years. According to the WHO, 10-15% of couples have some fertility problem and 25-50% of this is due to anovulatory female infertility, which could be due to insulin resistance, especially in overweight and obese patients, since 75% of obese patients suffer from IR, added to the fact that overweight and obesity have a high prevalence in the Mexican population, where a prevalence of up to 35% has been reported, it is important to consider it as a causal factor in patients with infertility. In 2021, 413 first-time patients with a diagnosis of infertility were received at the Gynecology-Obstetrics UMAE of CMNO IMSS; of these, 245 have a diagnosis of anovulation and about 40% are overweight or obese, however, there is no report on reproductive outcomes of these patients who undergo medical treatment, some cases achieve clinical pregnancy and of these some result in term births, preterm, miscarriage and / or death. Infertility and obesity have a great impact on women's health, affecting the physical, psychological, family and social area, leading to a deterioration in the quality of life, in turn obesity is one of the main risk factors for numerous diseases, so they are of special interest to social level and in the health system, being important its study and treatment to achieve better results of fertility and health in general.