Weil's Disease Early Diagnosis and Management: A Case Report

Abstract: Introduction: Leptospirosis, or Weil's disease, is the most common zoonotic infection. Weil's disease is caused by infection with the spirochete bacterium Leptospira. Acute kidney injury (AKI) is a common condition that often occurs in the final stages of Weil's disease. Although there is no definite consensus on renal replacement therapy (RRT) in severe leptospirosis patients, early diagnosis allows for earlier hemodialysis, which appears to be associated with a better prognosis. Therefore, this case report will present a case of Weil's disease undergoing hemodialysis as early management. Case Description: A 64-year-old male patient came to Buleleng Regional Hospital on May 15, 2023, complaining of yellowing of the eyes and skin for 7 days. The patient had also experienced nausea and vomiting for 7 days. The patient also complained of fever for 10 days. Supportive examinations were non-reactive anti-HCV and reactive anti-Leptospira IgM. The patient was diagnosed with Weil's disease, acute kidney injury (AKI), with a differential diagnosis of acquired cystic kidney disease (ACKD) and anuria. Conclusion: Patients with leptospirosis infection are generally associated with kidney involvement related to the need for hemodialysis, which can increase mortality. Therefore, early diagnosis and management in the form of hemodialysis is needed to improve quality of life and reduce mortality. Keywords: hemodialysis, leptospirosis, Weil's disease. Title: Weil's Disease Early Diagnosis and Management: A Case Report Author: Ni Komang Rani Juli Antari, Dwiputra Yogi Pramarta International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Vol. 13, Issue 1, April 2025 - September 2025 Page No: 49-54 Research Publish Journals Website: www.researchpublish.com Published Date: 23-April-2025 DOI: https://doi.org/10.5281/zenodo.15269210 Paper Download Link (Source) https://www.researchpublish.com/papers/weils-disease-early-diagnosis-and-management-a-case-report