Modeling HIV Reservoir Reduction and Functional Cure Probability Under a Cyclic Resveratrol + NAC Protocol

This document presents two modeled projections supporting the proposed cyclic Resveratrol + NAC protocol for latent HIV reservoir reduction. The first figure shows expected reservoir decay over up to 30 treatment cycles under varying per-cycle reduction rates. The second figure estimates functional cure probability as a function of residual latent reservoir size. These figures complement the white paper: “Cyclic Oral Resveratrol and NAC Therapy for Progressive Reduction of Latent HIV Reservoirs in ART-Suppressed Individuals” (DOI: 10.5281/zenodo.15390537).

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-16
DOI
https://doi.org/10.5281/zenodo.15431916
Primary Topic
Sirtuins and Resveratrol in Medicine
Type
article
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article

Modeling HIV Reservoir Reduction and Functional Cure Probability Under a Cyclic Resveratrol + NAC Protocol

Zenodo (CERN European Organization for Nuclear Research)
Sirtuins and Resveratrol in Medicine
article

Modeling HIV Reservoir Reduction and Functional Cure Probability Under a Cyclic Resveratrol + NAC Protocol

article en

Abstract

This document presents two modeled projections supporting the proposed cyclic Resveratrol + NAC protocol for latent HIV reservoir reduction. The first figure shows expected reservoir decay over up to 30 treatment cycles under varying per-cycle reduction rates. The second figure estimates functional cure probability as a function of residual latent reservoir size. These figures complement the white paper: “Cyclic Oral Resveratrol and NAC Therapy for Progressive Reduction of Latent HIV Reservoirs in ART-Suppressed Individuals” (DOI: 10.5281/zenodo.15390537).

Zenodo (CERN European Organization for Nuclear Research)
Society of Critical Care Medicine (US)
Good health and well-being
Openalex Percentile: Top 44%
Sirtuins and Resveratrol in Medicine
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