DESIGNING HUMAN MACHINE INTERFACE FOR DNA COMPUTING

The biological DNA (Deoxyribose Nucleic Acid) is being increasingly considered as an alternative processor to a silicon chip. DNA-based logic circuits are an attractive alternative to silicon-integrated circuits in specific control applications. Developing models for Boolean operations using DNA strands requires computer science and biochemistry expertise. However, there is a vast gap between the user who needs computation using DNA and the various DNA operations to be carried out with the help of Microarray, Microtiter plate and their respective Reader. In this paper, an HMI (Human machine interaction) is modelled for solving Boolean logic circuit and combinatorial optimization problems. An HMI is designed with the digital screen as the interface between the user and the bio-operations in the wet lab. The interface transforms the input from the user to DNA strands and the bio-operations to be carried out to achieve the desired solution. An attempt is made in this paper to design HMI for getting the inputs, followed by the DNA encoding of the inputs. The various bio-operational steps to be carried out in the wet lab and finally to read the output from the Microarray or Microtiter plate Reader and to be viewed in the digital screen by the user.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-30
DOI
https://doi.org/10.5281/zenodo.15772354
Primary Topic
DNA and Biological Computing
Type
article
Field-Weighted Citation Impact
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article

DESIGNING HUMAN MACHINE INTERFACE FOR DNA COMPUTING

Zenodo (CERN European Organization for Nuclear Research)
DNA and Biological Computing
article

DESIGNING HUMAN MACHINE INTERFACE FOR DNA COMPUTING

article en

Abstract

The biological DNA (Deoxyribose Nucleic Acid) is being increasingly considered as an alternative processor to a silicon chip. DNA-based logic circuits are an attractive alternative to silicon-integrated circuits in specific control applications. Developing models for Boolean operations using DNA strands requires computer science and biochemistry expertise. However, there is a vast gap between the user who needs computation using DNA and the various DNA operations to be carried out with the help of Microarray, Microtiter plate and their respective Reader. In this paper, an HMI (Human machine interaction) is modelled for solving Boolean logic circuit and combinatorial optimization problems. An HMI is designed with the digital screen as the interface between the user and the bio-operations in the wet lab. The interface transforms the input from the user to DNA strands and the bio-operations to be carried out to achieve the desired solution. An attempt is made in this paper to design HMI for getting the inputs, followed by the DNA encoding of the inputs. The various bio-operational steps to be carried out in the wet lab and finally to read the output from the Microarray or Microtiter plate Reader and to be viewed in the digital screen by the user.

Zenodo (CERN European Organization for Nuclear Research)
Industry, innovation and infrastructure
Openalex Percentile: Top 52%
DNA and Biological Computing
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DESIGNING HUMAN MACHINE INTERFACE FOR DNA COMPUTING · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS