Quality Control and Shelf-Life Study of Dasmula Taila- A Classical Ayurvedic Formulation for Nasya

Background: In Ayurveda, medicated oils are primarily employed to address ailments related to Vata Dosha imbalance. Dasmula Taila, a classical formulation mentioned in Bhaisajya Ratnavali, is used for managing Shiro-roga (head diseases) and nasya (administration of medicament through nostrils). Objectives: Methods: The key ingredients include roots of Bilva (Aegle marmelos (L.) Corrêa), Shyonaka (Oroxylum indicum (L.) Kurz), Gambhari (Gmelina arborea Roxb), Patala (Stereospermum suaveolens (Roxb.) DC), Agnimantha (Clerodendrum phlomidis Linn), Shalaparni (Desmodium gangeticum (L.) DC), Prishniparni (Uraria picta (Jacq.) Desv), Kantakari (Solanum xanthocarpum Schrad. & H. Wend), Brihati (Solanum indicum Linn), Goksura (Tribulus terrestris L.) and murchit Tila Taila. Rich in Tridosha-calming substances, it is prepared by using the traditional Taila-paka method, a form of oil preparation detailed in ancient Ayurvedic texts, and adheres to the prescribed procedures outlined in the Ayurvedic Pharmacopoeia of India (API). The organoleptic study and physicochemical analysis have provided valuable information towards the development of quality control data of the formulation. Also the chemical standards of the formulation were developed using sophisticated analytical techniques like high performance thin layer chromatography (HPTLC) study. Results: As no detail study on the quality control parameters of Dasmula Taila is available in existing literature, this study is essential to establish quality control benchmarks for the prepared Dasmula Taila formulation. In this regard Quality control data of three batches of Dasmula Taila was prepared along with HPTLC profiling. Accelerated shelf life study was also carried out to access its stability and the data suggests that the formulation is stable for at least for 6 months.