The Biochemistry of Aging: Unlocking the Secrets to a Longer, Healthier Life

Aging is an inevitable biological process characterized by a gradual reduction in physiological functions and an increased susceptibility to diseases associated with aging. At the molecular level, it results from a complex interaction of genetic, environmental, and lifestyle influences. Essential biochemical processes involved include oxidative stress, mitochondrial dysfunction, DNA damage, epigenetic alterations, and cellular senescence. A deeper understanding of these mechanisms provides insight into potential interventions that may promote healthy aging and increase lifespan. This article explores the fundamental biochemical principles of aging, emphasizes key mechanisms, and investigates new strategies aimed at reducing age-related decline.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-16
DOI
https://doi.org/10.5281/zenodo.15227069
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
Field-Weighted Citation Impact
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article

The Biochemistry of Aging: Unlocking the Secrets to a Longer, Healthier Life

Zenodo (CERN European Organization for Nuclear Research)
Genetics, Aging, and Longevity in Model Organisms
article

The Biochemistry of Aging: Unlocking the Secrets to a Longer, Healthier Life

article en

Abstract

Aging is an inevitable biological process characterized by a gradual reduction in physiological functions and an increased susceptibility to diseases associated with aging. At the molecular level, it results from a complex interaction of genetic, environmental, and lifestyle influences. Essential biochemical processes involved include oxidative stress, mitochondrial dysfunction, DNA damage, epigenetic alterations, and cellular senescence. A deeper understanding of these mechanisms provides insight into potential interventions that may promote healthy aging and increase lifespan. This article explores the fundamental biochemical principles of aging, emphasizes key mechanisms, and investigates new strategies aimed at reducing age-related decline.

Zenodo (CERN European Organization for Nuclear Research)
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Genetics, Aging, and Longevity in Model Organisms
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