Smart Drug Delivery Systems In Veterinary Medicine

Smart drug delivery systems (SDDS) are revolutionizing veterinary pharmacology by offering advanced solutions to the limitations of conventional drug administration in animals. These technologies, including nano-formulations, long-acting injectables (LAIs), and smart-release systems, aim to enhance drug bioavailability, reduce dosing frequency, and improve treatment compliance, particularly in livestock and companion animals. SDDS contribute to better therapeutic efficacy, minimized stress in animals, and improved public health through controlled drug use. Nano-based carriers enhance solubility and cellular uptake, while LAIs enable sustained therapeutic levels for extended periods. Smart-release systems respond to physiological triggers such as pH or temperature, releasing drugs at the desired site of action. This article reviews the principles, advantages, and applications of these delivery systems, while addressing the regulatory and implementation challenges, with reference to recent advancements in veterinary science.Keywords: SDDS, veterinary, pharmacology, principles and drug.